3. a) Discuss
how erythrocyte and its pigments are related to their function.
b) Explain why haemoglobin molecules are not
found in blood plasma.
Answer:
a) - Erythrocytes function to transport oxygen and
some carbon dioxide.
- Erythrocyte are small,biconcave discs
with a diameter of 7-8 µm.This increases the surface area per volume ratio and
allow oxygen to diffuse quickly into or out of the cell.
- The elastic membrane of the erythrocytes
enable the erythrocytes to squeeze through the narrow blood capillaries.
- The cells
move in a single line and are closer to the capillary to diffuse rapidly
into the cell.
- Te
erythrocyteshave no nucleus,no organelles such as mitochondria and ER.
- There is
more space to contain haemoglobin,increasing the amount of oxygen which can be
carried by he erythrocytes,There are about 250 million haemoglobin molecules in
each erythrocyte.
- Since the
erythrocyte are small cells,the haemoglobin molecules are not far from the
plasma membrane and its source of oxygen.
-
Haemoglobin has a quartenary structure.It is made up of four polypeptide
chains,each chain has a haem group containing iron.Each molecule of haemoglobin
can therefore combine with four oxygen molecules.
- Some carbon
dioxide (10%) can combine with haemoglobin to form carbaminohaemoglobin which
is carried by the erythrocytes.
b) ~ If
haemoglobin were suspended in the plasma rather than enclosed within
erythrocytes,the blood would become too viscous for the heart to the heart to
pump the blood through the blood vessels.
~
Haemoglobin would also affect the solute potential In the blood.
~ Membranes of Bowman’s capsule in the nephron
allows only proteins of molecular weight below 68000 to pass.The haemoglobin
molecules are smaller than 680000 threshold molecule weight.If present in the
plasma,the haemoglobin can pass through the fitration membrane and be lost in
the urine.
Assignment submitted by group chee tian 2011/2012 (IBM)
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