26. Describe briefly the primary, secondary and
tertiary structure of proteins. State the important of these structures which
are related to the properties of proteins. [11]
Answer:
A)
Primary
structure:
-sequences of amino acid in the polypeptide
chain.
-polypeptide chain consists of
amino/N-terminal and carboxyl/-terminal.
-numbering of sequence starts from
N-terminal.
-the amino acids are linked by peptide
bonds
-total amino acid/R-group/
side-chain/functional group determine protein to be basic, acidic or neutral/
soluble/ insoluble.
Secondary Structure:
-depends on hydrogen bonds.
-Produces α-helix and β-pleated structure.
-α-helix gives high elasticity/ cylindrical
structure/ coiled in the helical structure.
-β-pleated is for padding and cushion.
-both structures may be present in a
protein.
Tertiary Structure:
-depends on disulphide bridge/ bonds.
-hydrophobic interaction/ bond, ionic bond
and Van der Waals effect.
-forming globular structure gives/
determines biological activity
destroyed.
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