Wednesday, August 1, 2012

STPM Biology - chapter 3: Revision essay question 2


Describe the role of proteins , glycolipids and cholesterol in the structure of the cell 
surface membrane .

Answer

The cell surface membrane is composed of a phospholipid bilayer and along the membrane , there are numerous protein molecules , which are arranged in a mosaic pattern . Due to the phospholipid bilayers , the membrane is said to be selective or semi-permeable to certain substances . Proteins that are found along the cell membrane also play a role in transporting water-soluble ions across the membrane by the process of facilitated diffusion . These proteins form channels by which ions are able passes through the cell surface membrane . Other roles of the proteins in the membrane are to give structural support for the cell surface membrane , to allow calls to recognized by other agents ( e.g. enzymes , hormones and antibodies ) and to assist in the active transport of materials across the membrane . 
Glycolipids are carbohydrate chains attached to the surface of the membrane and generally perform two roles :
(1)  They allow cells to be recognized by other calls and agents in the body , as well as receptor sites for chemical signals . For example , the human ABO blood system is the result of different glycolipids on the cell surface membrane of the red blood cells .
(2) They also serve to stabilize the membrane structure .
The role of cholesterol is to act as a plug for reducing the entry and exit of polar molecules across the cell surface membrane and make the membrane more stable . Cholesterol also functions to make the cell surface membrane more flexible and fluid by disturbing the packing of phospholipids to prevent rigidity .

Assignment submitted by L.E., Teh, E.L., Wong, Tan Findy 2011/2012 (IBM)

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