1. Describe the sequence of events occurring during muscle contraction. [9]
Answer:
1. * Please refer to notes chapter 10: Action Potential and muscle contraction & Breakdown of ATP
and Cross-Bridge Movement During Muscle Contraction
-Transmission of impulse along the T tubule to the sacroplasmic vesicle
- secretion of Ca2+ ions by the sacroplasmic vesicle 1 calcium ions, bind to troponin
- troponin displaces tropomyosin / troponintropomyosin complex
- cause exposure of binding sites on actin
- myosin heads attach to actin filament
- myosin head contain ATPase
- myosin head changes position / actin filaments slide past myosin filaments
- myosin detaches from actin filament
- ATP cause this release /hydrolysis of ATP occurs to release energy to form and reform cross bridge /
myosin head cocked
- ratchet mechanism
- process continues provided enough ATP / calcium ions present
- AVP ; e.g. I band shortens , Z lines closer together, H zone shortens / sarcomere shortens , A band
- remain constant
- when there is no longer an impulse the Ca2+ ions re-enter the vesicle and the sacromere stop
contraction
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